Pieter Stubbe
From Tardis Wiki, the free Doctor Who reference
Pieter Stubbe was a German mass murderer who was sentenced to death in 1589. Unbeknownst to the townspeople, Stubbe was also a werewolf. He fled rather than die.
Stubbe continued to roam Europe for the next few centuries. He was in Russia in 1812; there, he turned Ileana de Santos into a werewolf.
By 2080, Stubbe's pack--mostly Ileana and her family--was living in ecologically devastated Brazil. Stubbe was lured there and defeated by the Fifth Doctor and Turlough.
