Y

From Tardis Wiki, the free Doctor Who reference
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As spoken by Sarah Jane Smith, Y was the twenty-fifth letter of the alphabet, following X and preceeding Z. (TV: The Masque of Mandragora, Goodbye, Sarah Jane Smith)

It was this letter which distinguished Lynda Moss, or "Lynda with a Y", from fellow Big Brother housemate "Linda with an I." (TV: Bad Wolf)