Guilt

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The Teller's telepathy allowed it to detect guilt. (TV: Time Heist)

Bennett, an escaped criminal, (AUDIO: The Crash of the UK-201) killed the survivors of the crash of the UK-201 to conceal his guilt. (TV: The Rescue)

The Valeyard attempted to prove the Sixth Doctor's guilt during the latter's trial. (TV: The Mysterious Planet, Mindwarp, The Ultimate Foe)

C'rizz felt guilty for killing L'da, as he was unsure as to whether he acted in compassion or panic. (AUDIO: Faith Stealer)

The Eleventh Doctor felt guilty for his effect on the lives of Rose Tyler, Martha Jones and Donna Noble. (TV: Let's Kill Hitler)

The Eleventh Doctor thought that empathics were some of the nicest and loneliest people that one could meet due to their exposure to the guilt, sorrow and pain of others. (TV: Hide)

In his diaries, Winston Churchill admitted to feelings of guilt regarding Coventry, (AUDIO: Hounded) which was heavily bombed by the Luftwaffe during the Blitz. Churchill was rumoured to have foreknowledge of the raid but stayed quiet to protect a secret code. (PROSE: This Town Will Never Let Us Go)

The First Doctor felt guilty for the fate of Troy during the Trojan War after he helped the Greeks built the Trojan Horse just to save Vicki. By his second incarnation, he also felt guilt regarding the death of Katarina. (AUDIO: Daughter of the Gods, TV: The Myth Makers, The Daleks' Master Plan)

Rachel Zimmerman believed guilt to be the strongest human emotion. In her words, guilt could turn a person inside out. (AUDIO: No More Lies)