British Royal Family
The British Royal Family were the family of the kings and queens of the United Kingdom.
Queen Victoria had haemophilia, a mutation which she didn't inherit from either of her parents. The Tenth Doctor jovially suggested the "royal disease" was actually werewolf cells which she passed to her children. They might eventually mature in the 21st century. (TV: Tooth and Claw)
Over the years, people identified numerous suspects as Jack the Ripper, including members of the Royal Family. (PROSE: The Pit) Amy Pond had been sure it was someone from the Royal Family. The Eleventh Doctor blamed this on movies and said it made the truth look less far-fetched in comparison. (COMIC: Ripper's Curse)