Patience

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Patience was the wife of Omega, the Other and the Doctor.

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Patience was born in the House of Blyledge on Gallifrey, one of the last Womb-born Gallifreyans. She was a young woman when the Pythia cursed Gallifrey with sterility. Her husband, one of the first to explore the Time Vortex, married her upon his return to Gallifrey. She was widowed when Omega disappeared after causing Qqaba to go supernova.

Omega himself was thought dead. In actuality, he had entered an anti-matter universe. (DW: The Three Doctors)

Patience became the Other's nurse and tutor. They fell in love, got married, and had thirteen children. When the Lord President of that time targeted the Other's family, the Other took Patience to the Machine for safety. The Machine crashed on an ice planet, where it was eventually found by Human colonists in the 26th century. (MA: Cold Fusion)

The Other threw himself in a Loom in order to reincarnate as a future Time Lord, which he did as the newly Loomed Doctor. (NA: Lungbarrow) The Doctor retained only fragmentary memories of the Other's incarnations.

It is unknown what order the Other experienced the above events in. If the events of the flashback in Cold Fusion occurred before the events of the flashbacks in Lungbarrow, this would contradict the Other's implication in the latter that he cannot regenerate, as the character in the Cold Fusion flashback is implied to have regenerated. If the Lungbarrow flashbacks come first, this would seem to suggest that the Other seen in the Cold Fusion flashbacks was a reincarnation of the Other before the First Doctor.

Patience, meanwhile, regenerated shortly after the Doctor discovered her. Provost-General Tertullian Medford, believing Patience to be a threat, shot her in the head, and her body vanished. (MA: Cold Fusion)

Patience hadn't died. She was rescued by Omega, who took her to the anti-matter universe. The Doctor was reunited with her there, but lost her again soon afterwards. (PDA: The Infinity Doctors)