The Carsenome was the base of the Animus. It was manned by its Zarbi servants. The Animus used a long tube in the Carsinome to talk to the First Doctor. The Zarbi took the Doctor's TARDIS there. The Doctor set up communications equipment in the Carsinome on the Animus' orders. (TV: The Web Planet)
After the Isop-tope device reduced the Carsinome to a single tendril, it regrew as the Animus "beg[a]n again" on Earth, reforming in the London Underground in 1868. The Carsinome was killed when Ian Chesterton drove a train into it. (COMIC: Prisoners of Time)
Behind the scenes
The spelling "Carsinome" originates from the script of TV: The Web Planet. COMIC: Prisoners of Time uses the spelling "Carsenome". Doctor Who and the Zarbi simply calls it "the Centre" or "the Zarbi Headquarters".