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The wheel was an invention in humanity's early history, used for transportation. The Silents claimed to have watched humans on Earth since the wheel and the fire. (TV: Day of the Moon)
When Ian Chesterton expressed his bewilderment at the First Doctor's description of his police box-shaped home as a "ship", the Doctor sarcastically told him that "this doesn't roll along on wheels, you know." (TV: An Unearthly Child)
The Go-Rays had a single toothed wheel at the bottom of their bodies which they used for locomotion. (COMIC: Enter: The Go-Ray)