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A bow tie was a type of men's necktie in the shape of a bow. They could be either pre-tied or self-tied. The Doctor wore a bow tie in many of his incarnations, though the traditional bow tie was most often associated with the Second and Eleventh Doctors.
The Second Doctor's bow tie appeared along with his other clothes when his first incarnation regenerated with the TARDIS' assistance. As with the rest of his clothing, the Second Doctor's bow tie was untidy and crumpled; it was a small pre-tied dark tie with small spots, attached to his collar with a safety pin.
The Third Doctor wore a variety of accessories, including bow ties. These were chosen to match his various outfits, and he had several in different sizes and colours. (TV: The Three Doctors, Invasion of the Dinosaurs etc.)
Sir Keith Gold, the Executive Director of the Inferno Project, was also seen to wear a bow tie. (TV: Inferno)
The Tenth Doctor usually wore a necktie, but on some occasions dressed up in formal wear, including a bow tie. (TV: The Lazarus Experiment, Voyage of the Damned)
The Eleventh Doctor adopted a bow tie along with the other clothes he stole from Royal Leadworth Hospital soon after his regeneration. (TV: The Eleventh Hour) He would often insist that "bow ties are cool" in spite of his companions' disagreement. (TV: The Eleventh Hour, Vincent and the Doctor, The Lodger, A Christmas Carol, et al.) He also included a white bow tie as part of his formal wear, seen during Amy and Rory's wedding (TV: The Pandorica Opens) and on the occasion of his death (TV: Let's Kill Hitler). During his period of retirement after losing Amy Pond and Rory Williams, the Eleventh Doctor changed his outfit to something more befitting his sojourn in Victorian London, but put on a bow tie again when spurred back into adventure by Clara Oswald. (TV: The Snowmen) Before his regeneration into the Twelfth Doctor, he removed it and let it drop to the floor. (TV: The Time of the Doctor)
Having received a glimpse of his eleventh incarnation through his psychic paper in 2724, the Second Doctor described his bow tie as "rather fetching." (AUDIO: Shadow of Death) By contrast, when the Fourth Doctor witnessed a statue of his future self, he expressed disbelief at his future incarnation's choice of attire (PROSE: The Roots of Evil).