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The Butler Institute was a human business corporation in the early 21st century headquartered in New York City. The company was secretly researching techniques for transfering human consciousness into computers as a means of avoiding the hazards of climate change and social collapse around the world, but this plan was defeated by the Seventh Doctor. (PROSE: Cat's Cradle: Warhead)
In 2009, the Butler Institute building was not harmed by the atmospheric-cleaning fire created by the Tenth Doctor to avert the Sontaran invasion of Earth. (TV: The Poison Sky)
In 2107, the Butler Institute merged with Eurogen Company to form the EB Corporation. (PROSE: Deceit)
Behind the scenes
In the novel, the Butler Institute building is described as having at least seventy-four floors, while the TV version seems to be significantly smaller.