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Margaret Blaine was a senior member of MI5 in the early 21st century. At some point prior to April 2006, Blaine was murdered by Blon Fel-Fotch Passameer-Day Slitheen, who used her skin to impersonate her. (DW: Aliens of London) Still posing as Blaine, the Slitheen ran for mayor of Cardiff. (DW: Boom Town)
Behind the Scenes
Technically, Margaret Blaine never appeared in Doctor Who, only Blon Fel-Fotch Passameer-Day Slitheen masquerading as her. However, the credits for Aliens of London/World War Three and Boom Town credit the character by her alias of Margaret Blaine.