The Genetic Manipulation Device was invented by Richard Lazarus. The machine would turn anyone inside decades younger, but at one side effect: genes that evolution rejected and left dormant would be unlocked, transforming the human into a giant skeletal scorpion-like beast that feeds off the juices off living creatures.(DW: The Lazarus Experiment)
Harold Saxon (a.k.a the Master) supported Lazarus's research so that he could copy, improve and focus all that technology in his Laser screwdriver and reverse it to age people forward.