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Agrofuel Research Operations was a laboratory located in Yorkshire.
In 2017, Douglas and Erica were working with a sample of R planticola. However, Douglas misplaced a decimal point while specifying the dosage of the EC 31 enzyme, which resulted in an airborne bacterium that could quickly destroy plants and even kill a human just by being exposed to it.
The lab was on the UNIT watchlist and the Monks had predicted that within a year, the bacteria created at the lab would wipe out all life on Earth. With the help of Nardole, the Twelfth Doctor determined the lab to be the location of the world-ending bacteria. Before the lab's automatic venting procedure would release the bacteria into the atmosphere, the Doctor set off an explosion that destroyed half the lab and sterilised the bacteria. (TV: The Pyramid at the End of the World)