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The Alphans were a species of dark-skinned humanoids from Thoros Alpha. They were genetically incompatible with the amphibian Mentors of Thoros Beta in terms of tissue transplants.
Many Alphans were taken from Thoros Alpha by the Mentors, for use as menial labour and experiments. These slaves were kept in special storage facilities when they were not being used. By 2379, some of the Alphans were able to escape control and tried to form a resistance. Though the Mentors knew of this, they believed that the Alphans were harmless and were unable to properly use the weapons they were stockpiling. (TV: Mindwarp)