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In a parallel universe, the Alpha Quadrant was a quadrant of the Milky Way galaxy. The United Federation of Planets was based in the Alpha Quadrant. (COMIC: Assimilation²)
Behind the scenes
In the Star Trek universe, the galaxy is divided into four quadrants. Earth is located in the Alpha Quadrant, with the United Federation of Planets having territory in both the Alpha and Beta Quadrants. There is also the Gamma Quadrant, primarily featured in Star Trek: Deep Space Nine. The Delta Quadrant is primarily featured in the spin-off series Star Trek: Voyager, where the titular starship travels through the quadrant throughout the show's run in order to get back home.