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Global destruction refered to the destruction of planets.
The Seventh Doctor seemingly caused the destruction of Skaro by having the Hand of Omega induce a supernova in its sun, causing the planet to vapourise. (TV: Remembrance of the Daleks)
Having destroyed twelve planets, Androvax was charged with twelve counts of global destruction, as noted by the Judoon Captain Tybo. (TV: Prisoner of the Judoon)
In 5,000,000,000, Earth met its natural destruction at the hands of the expanding star Sol in an event known as Earth Death. (TV: The End of the World)