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Title
Issue 421 was published 29 April 2010, in between The Time of Angels and Flesh and Stone.
Articles
- Exclusive Previews: The Vampires of Venice, Amy's Choice, and The Hungry Earth/Cold Blood
Profiles / Interviews
- Alex Kingston - who is River Song?
- Terrance Hardiman - the difference between The Demon Headmaster and Doctor Who?
Comic Strip
- Supernature - Part 1
- - Story: Jonathan Morris
- - Pencil Art: Mike Collins
- - Inks: David A. Roach
- - Colours: James Offredi
- - Letters: Roger Langridge
- - Editors: Tom Spilsbury and Scott Gray
The Fact of Fiction
The DWM Review
- The Eleventh Hour
- The Beast Below