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Disintegration was the utter destruction of an object or lifeform.
What appeared to be disintegrator beams were employed the Game Station in 200,100, where they were used to seemingly execute humans who lost the game shows there. Such beams were used by the Anne Droid of The Weakest Link and by Davinadroid within the Big Brother House. However, it was revealed that these disintegrators were actually transmats which transported the people to the Dalek Fleet for processing into Dalek of human origin. During the Battle of the Game Station, the Anne Droid was repurposed to fight the invading Daleks, managing to take out three of them before it was destroyed. (TV: Bad Wolf/The Parting of the Ways)
The Daleks of the New Dalek Paradigm used their gunsticks to disintegrate their predecessors. (TV: Victory of the Daleks)
At one point in their lives, the Doctor was stalked by Android Assassin armed with disintegrator blasters. Having earned their ire by stealing a teleport bracelet, the Doctor was able to use the energy from their Energy weapons to recharge the bracelet and teleport away, tricking the androids into thinking he had been disintegrated. (TV: The Witch's Familiar) During the Last Great Time War, the Eighth Doctor used this trick to escape a Dalek execution. (AUDIO: The Shoreditch Intervention) The Master learnt this trick and used it to escape death at least twice. (TV: Death in Heaven, The Witch's Familiar)