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Guido was the father of Isabella and a Venetian ship builder.
Biography
After successfully getting Isabella into Rosanna Calvierri's school, Guido discovered it was not what it seemed. He met the Doctor following a failed attempt to get his daughter back, and the two became allies. Guido feigned another attempt as a distraction to let the Doctor gain entry to the school. Later he explained to the Doctor how he had tried to use an underground passageway, but was blocked by a trap door. He offered to use the gunpowder he took from the shipyards while working on warships, but the Doctor refused.
As their plan failed again, the group regrouped in Guido's house and tried to plan what to do next. The house was attacked by all the female Saturnynian converts, and while the Doctor, Amy and Rory escaped, he remained behind. Guido then lead the converts to his gunpowder and shouted "We are Venetians" and he set light to it. The explosion killed everyone in the house, and ultimately doomed the Saturnynian species to extinction. (DW: The Vampires of Venice)
Since the cracks in time were extingwished, everything about the vampires including Guido's death may have not happend