The Crab Nebula was a nebula located within the galaxy of Mutter's Spiral. It was created by the Uxarieans by detonating a star with their Doomsday Weapon. (DW: Colony in Space) This is believed to have occurred either during the Millennium War circa 150 million BC (PDA: The Quantum Archangel) or circa 5300 BC (DW: Colony in Space). This supernova became visible on Earth in 1054. (DW: Colony in Space)
The planet Wengrol was located in the Crab Nebula. (DWA: The Sons of the Crab)
In the 51t century, humanity relocated to the Crab Nebula after Earth was ruined by solar flares. (DWM: The Keep)
The Tenth Doctor took Grayla to either the Crab Nebula or the Horsehead Nebula. (IDW: The Whispering Gallery)