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Uncle was a patchwork person who helped House lure Time Lords and their TARDISes to him.
Biography
Uncle found himself on House when a temporal rift caused him to be transported there. On the asteroid, he lived with Auntie, Nephew and Idris. Like Auntie, he was made mostly of snatched body parts from Time Lords and other creatures that were also transported to House. He had a rather sober disposition and tended to make dark jokes and surly remarks.
Both he and Auntie died when House left the asteroid as they both relied on it for their life sustaining functions. Faced with their imminant death, Uncle and Auntie remained stoic and unfazed, though Uncle admitted that he was "against it". He died shortly after Auntie, decaring "Actually, I feel fine", before suddenly collapsing dead.
Uncle's age is unknown, but he may have been in his fifties, as the Doctor noted that he had the eyes of a twenty-year-old, but that the rest of his body was thirty years older. However, Uncle may not have had any of his original body intact by the time the Doctor arrived. Aside from the eyes, by the time he died, he had an alien right ear, his right arm was two inches longer than the other, and he had two left feet. At some point in the past, he aquired The Corsair's spine and kidney's after House lured him onto the asteroid. (DW: The Doctor's Wife)