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Chen-7 (also known as the 1 Day Plague) was a deadly plague. It could kill in 1 day and was only contractable by species with a binary vascular system, such as the Apalapucians and the Gallifreyans.
When a Chen-7 plague threatened Apalapucia, the Apalapucians created the Two Streams facility, which used temporal technology to isolate the patients and stretch out the day into a lifetime. (DW: The Girl Who Waited)