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Chen-7 (also known as the One Day Plague) was a deadly plague that could kill in one day and was only contractable by species with a binary vascular system, such as the Apalapucians, the Gallifreyans and the Time Lords.
When a Chen-7 plague threatened Apalapucia, the Apalapucians created the Two Streams facility, which used temporal technology to isolate the patients and stretch out the day into a lifetime. (DW: The Girl Who Waited)