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Mrs. Angelo was the grandmother of Jeff Angelo. She was disturbed when the Atraxi hijacked and appeared on her television and even more so when Amy Pond and the Eleventh Doctor burst into her home. She commented that she had seen the Doctor before, but he replied that it was not him, because he had just regenerated: Not me. Brand new face. (DW: The Eleventh Hour) This might mean that she and the Doctor will meet again in the future.