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The Imperiatrix was a title held by the first female ruler of the Time Lords, a woman known as Pandora. The Imperiatrix personal guards were known as the Imperial Guard. (BFG: Imperiatrix, Lies)
In one possible reality caused by the influx of Anti-Time, Romana II held the position of Imperiatrix of the empire of Zagreus, keeping the Dalek Emperor captive, and threatening the Dalek race with destruction. (BFA: Neverland)
