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The "Final Experiment" was an experiment by the Cult of Skaro to create a New Dalek Empire, initiated whilst they were in 1930s New York. The study of the Final Experiment was to see if a Dalek could bond with a Human to create a Human-Dalek hybrid.
It was headed by Dalek Sec who served as the subject. He bonded with the Cult's human connection Mr Diagoras and through a "chromatid solution", the final outcome was the Human-Dalek. The Dalek-Humans would have been made as the New Daleks had Dalek Caan not led a mutiny against Sec.(DW: Daleks in Manhattan)