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Tsarevich Alexei Romanov was the young son of Tsar Nicholas II and Tsarina Alexandra of Russia.
He inherited haemophilia through his blood relation to Queen Victoria of Great Britain. (PROSE: The Clockwise Man) The Tenth Doctor and Rose Tyler speculated that Victoria developed the disease, potentially a form of lycanthropy, after being bitten by the Lupine Wavelength Haemovariform. (TV: Tooth and Claw) Indeed, Alexandra too noted that the haemophilia in Alexei worsened when a "second moon [arrived] in the sky". (TV: The Power of the Doctor)
He was the male heir to the Russian throne but was killed with his parents and sisters following the revolution, (PROSE: The Clockwise Man) on 16 July 1918 in Ekaterinburg. (AUDIO: Last of the Romanovs)