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Dehydration resulted from a lack of fluid in the body. During his experiments (TV: The Sontaran Experiment) in 16087, (AUDIO: Wirrn Isle) Styre noticed that humans would lose their mental and motor skills if they did not drink fluids. (TV: The Sontaran Experiment)
The Ninth Doctor scanned Rose Tyler with his sonic screwdriver upon retrieving her from the Zreeg's domain, and discovered that she was severely dehydrated, with an "abysmal" electrolyte count. (PROSE: The Monster in the Cupboard)