Charles Griffiths accused Gustave Lytton of an insult. (TV: Attack of the Cybermen)
The inhabitants of the planet Dyssiopeia communicated exclusively through insults. Clara Oswald however managed to utter a phrase that offended even them. (COMIC: Planet of the Rude)
Clara later accidentally insulted the monarch of Planet Karaoke when she attempted to sing in Karaokean without the aid of the TARDIS' translation circuits. (COMIC: The Meddling of Clara's Song)