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The metabolism detector was a mechanism in the Doctor's TARDIS which allowed no one to enter it with the TARDIS key except for the Doctor. Brigadier Lethbridge-Stewart failed in his attempt to open the TARDIS door due to the detector. (TV: Spearhead from Space [+]Loading...["Spearhead from Space (TV story)"])
In a parallel universe, the Doctor's TARDIS had a metabolism detector in the lock. Lee was unable to gain entrance into the TARDIS. (AUDIO: Full Fathom Five [+]Loading...["Full Fathom Five (audio story)"])