Paralysis
Paralysis was the inability to move. Sutekh was imprisoned and paralysed in a tomb on X, he used Marcus Scarman as his arms and legs to free himself. (TV: Pyramids of Mars)
Paralysis could occur from particularly violent movement or experiences; the Fourth Doctor was concerned that Sarah Jane Smith was paralysed following the two of them being caught in a quarry mine explosion. (TV: The Hand of Fear) Whilst violent physical fighting and contact with points like the solar plexus could leave humans momentarily paralysed. (PROSE: Blood Harvest)
Biologically induced paralysis
Paralysis could also result from biological contact with several substances being able to induce it. Unprotected contact with a spectrox nest resulted in spectrox toxaemia; beginning with a rash, followed by spams then slow paralysis of spinal nerves and finally thermal death point. (TV: The Caves of Androzani)
Tetrodotoxin was a naturally occurring and highly potent neurotoxin, symptoms poisoning by it included pulmonary oedema, hypotension, cyanosis, hypothermia, respiratory distress, paralysis and death. (PROSE: Cat's Cradle: Warhead)
Paxx-Sinopli syndrome resulted in partial paralysis and then eventual death from cerebral emancipation. (PROSE: Dark Progeny)
Biological paralysis was not always fatal, sleep paralysis was a method by which the human body prevented humans acting out their dreams whilst asleep. (PROSE: Dry Pilgrimage)
Technologically induced paralysis
Weapons technology could also be used to paralyse, the Sensorites', the Quarks' and the Daleks' weapons could be used to paralyse individuals. (TV: The Sensorites, The Dominators, 'The Daleks)
Earth-based technology could also induce paralysis, through the use of a taser gun or a stun gun an individual could be stunned or paralysed unable to move. (PROSE: Just War, Eternity Weeps, TV: End of Days)