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The Z-Neutrino Biological Inversion Catalyser was a device created by the Meta-Crisis Tenth Doctor shortly after his 'birth'. It was created from pieces of the TARDIS and was designed to lock the transmission of the Reality bomb onto Davros, killing him and the Daleks that he had grown from his own cells. The Meta-Crisis Tenth Doctor arrived on the Crucible with the intention of destroying the Daleks of the New Dalek Empire but before he could fire the weapon, he was incapacitated by an energy bolt from Davros' cybernetic hand. Donna also attempted to use it but was also incapacitited by Davros while asking how to fire it. Upon Davros' orders the Inversion Catalyser was then destroyed by a Vault Dalek.