Ubersoldaten
The Ubersoldaten was an umbrella term to describe the genetically and cybernetically re-engineered young Human super-soldiers that saw service during the Thousand Day War against the Ice Warriors. The modifications included augmented nervous systems, increased strength, enhanced reflexes and spatial perceptions, all of which could be further boosted via specially designed combat drugs. However, the people undergoing these procedures were deliberately sterilized to prevent the biological and legal problems that would arise from pasing on corporately-owned genetic sequences to their offspring.
In the years following the war, one of the companies responsible initiated the development of a second generation of ubersoldaten whose enhancements -- including strength, reflexes, recuperation and nutritional efficiency -- were entirely biological. While the technology involved was presumably human-devised, potentially augemented by reverse-engineered Ice Warrior science, the Seventh Doctor ruminated that the muscle structures programmed into the second generation's genome resembled those belonging to Time Lords of a bygone era.
Aware of this project but unwilling to interfere directly, an individual likely to be a future incarnation of the Doctor made contact with the hacker known as the Angel Francine, a veteran of the Thousand Day War. Using her contacts amongst her fellow veterans, she arranged for an armed raid on the eugenics facility that destroyed the projects's physical infrastructure and research data archives. However, the raid revealed that a single prototype had already been created; rather than being euthanased, the newborn was instead adopted and raised as Kadiatu Lethbridge-Stewart. (NA: Transit)