Mother of Mine
Mother/Wife of Mine was the matriarch of a criminal family known only as the Family of Blood. She resembled a gaseous entity prior to possessing Jenny, a maid from the Farringham School for Boys.
Her family attempted to take the Tenth Doctor's life essence. After they were defeated by the Doctor, Mother of Mine was thrown into the event horizon of a collapsing galaxy, to be shown how horrible it is to live forever. Her husband, son and daughter underwent similar punishments. (TV: Human Nature/The Family of Blood)
According to one account, Daughter of Mine managed to escape her imprisonment by possessing Nancy Latimer, and set her father and brother free as well. To free Mother of Mine, they captured the Doctor and Donna Noble in the Tardis, but the Doctor managed to escape his restraints and trapped the entire Family of Blood with Mother of Mine in the black hole, after freeing Nancy from possession. (PROSE: Blood Will Out)
Behind the scenes
Mother of Mine is one of the enemies in Doctor Who Legacy mobile game.