Validium
Validium was created as the ultimate defense for Gallifrey by Rassilon and Omega and had great destructive potential. It was living metal that could think for itself and was capable of speech as well. When destroyed, it could reform itself.
It should never have left Gallifrey, but some of it did. A piece of validium fell to Earth and was found by the Lady Peinforte, who molded it into a statue of herself holding a bow and arrow and called it Nemesis. The Doctor then launched the Nemesis into space on the rocket-sled, though the bow and arrow were kept on Earth. Its orbit had brought it near Earth every 25 years, each time causing disasters by remote influence. In his seventh incarnation, the Doctor arrived on Earth as it approached again in 1988.
Following the Doctor's instructions, the Nemesis was launched to rendevous with the Cybermen's fleet in Earth orbit and destroyed the fleet. It reformed in space and it is unknown what happened to it next. (DW: Silver Nemesis)
The Cold was made of this substance. (EDA: Interference - Book One / Interference - Book Two)
- Since Gallifrey has been destroyed, it is unknown if any validium remains in the universe.