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At the beginning of the Eleventh Doctor's life, he found himself in a version of his universe whose skin was cracking at every moment in time due to the explosion of the Doctor's TARDIS. (TV: The Pandorica Opens) These cracks erased things from existence, with many events from the Tenth Doctor's post-Time War universe undone. (TV: Flesh and Stone, PROSE: Student Bodies)
A crack in Amy Pond's house in Leadworth was responsible for the loss of her mother and father, Tabetha and Augustus Pond. As a result, she grew up with her Aunt Sharon. (TV: The Big Bang, The Eleventh Hour) The Doctor also implied that the cracks were responsible for a "duck pond" which was devoid of ducks. (TV: Flesh and Stone, The Eleventh Hour)
The Doctor became aware that Amy did not remember the earlier 21st century Dalek invasion, (TV: Victory of the Daleks) and also realised that "no-one remember[ed]" the CyberKing over Victorian London. (TV: Flesh and Stone)
During the 51st century crash of the Byzantium, a crack aboard the spaceship Byzantium, in succession, erased Church clerics Crispin, Marco, Pedro, Phillip. As Amy observed, these clerics did not realise the danger of the crack as it caused to them to forget those who had been erased, with the Doctor explaining to her that she remembered them because she was now a time traveller. Ultimately, this crack was closed after a number of Weeping Angels fell into it, forming a sufficiently complex space-time event to temporarily close the crack. (TV: Flesh and Stone)
Eventually, as the Doctor's present aligned with the moment of the TARDIS' explosion, this universe was nearly completely destroyed in a total event collapse, with the Starless World remaining as the eye of the storm. Using the few remaining particles untouched by the collapse, the Doctor was able to undo the damage by creating a rebooted universe in Big Bang Two. Events from the cracked version of reality carried over into this universe, (TV: The Big Bang) with some accounts indicating some events erased by the cracks were not restored. (PROSE: Dalek Combat Training Manual)
This reality continued to exist in some form as a dead timeline. Same and Different once visited this timeline in its final moments in Leadworth. (PROSE: The Paradox Moon)