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Mem-Brain fought against the Monaxi along with Sunzberro, Unta, Tony and Effrid Blunk for a long time, but he was captured by the Monaxi. Later, he was released from the Monaxi Circus. (COMIC: Medicine Man)
After Iktra activated a time bridge, he lost most of his memories. He found Jack Harkness, Cindy Wu, Cleo, Erik Ulfriksson, Muthmunna and Sunzberro and went looking for answers about what happened to them. (COMIC: Arena of Fear)