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This young girl (Melody Pond) was a previous incarnation of the Doctors mysterious companions River Song, she is known to be the daughter of Rory Williams and Amy Pond however due to the fact she was concieved in the Time Vortex (during Rory and Amy's wedding night) she contained D.N.A. the same or similar to that of a Time Lord.
Biography
The girl contacted Richard Nixon for assistance, but he did not know who was calling him. She told him about the "Monsters", and how she feared them.
When Nixon asked where or who she was, Melody (River) told him "Jefferson Adams Hamilton", leading him to believe her to be a boy. However, the Doctor realised these were the names of streets, the only three by those names intersecting in Florida, and probably all of America.
Melody (River) then watched from a distance when the Doctor arrived to find her. Whilst wearing what appeared to be an astronaut's suit, Melody eventually approached the Doctor and Amy Pond, the latter firing a gun at her own daughter (unaware that she was her daughter at the time), as she initially believed that she was the assassin of the Doctor, 200 years in his future, who wore a similar, if not identical, astronaut suit to her. (DW: The Impossible Astronaut)
Three months later Melody (River) again encountered Amy, who had only punctured the suit's visor, in what appeared to be her bedroom at the Graystark Hall children's home. The room contained a number photos of the Melody (River), including one of Amy holding an her as an infant . The Silence then appeared in the room behind the Melody (River) and took Amy hostage.
Melody (River) was able to free herself from the suit, which had been fitted with alien technology to act as a life support system, displaying enormous strength. She then ran from the scene after spying on the Doctor, Canton, River( her future incarnation) and Rory rushing to help Amy.
Six months later, her deteriorating health caused her to regenerate in a New York alleyway. (DW: Day of the Moon)