Helium
From Tardis Wiki, the free Doctor Who reference
Helium was a light element found on Earth. It was a gas at room temperature.
Arcturus's life support system included a helium regenerator, which, if deactivated, he would die. (TV: The Curse of Peladon)
When humans inhaled large quantities of helium, their voices became high-pitched. The Fourth Doctor was able to use his respiratory bypass system to avoid its effects. (TV: The Robots of Death)
Helium 2 had the potential to exist during the Leptonic Era. (TV: Time and the Rani)
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