River Nile
From Tardis Wiki, the free Doctor Who reference
The River Nile was in Egypt. The Doctor travelled down the Nile with Ediphis. The Osirian, Thoueris, hid in the Nile. She could control the Crocodiles in the Nile with a ring. (DWM: The Power of Thoueris!)
During the alternate timeline of The Year That Never Was, the Master had the Nile frozen over. (DW: Last of the Time Lords)
In another alternate timeline, penguins lived on the Nile. (DW: The Big Bang)