The Last Supper
From Tardis Wiki, the free Doctor Who reference
The Last Supper was a painting by Leonardo da Vinci. When the Fourth Doctor travelled to Florence in 1505 to talk to Leonardo, he mentioned how everybody loved it. (TV: City of Death)
In 2022, it was among fifteen different paintings that had been taken out of public view after being defaced, with Jesus Christ's face being replaced by that of the Spy Master in his Grigori Rasputin disguise. (TV: The Power of the Doctor)