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Snakes were a variety of reptiles.
History
Earth snakes
A snake from Brazil was one of the animals on board the Ark. (TV: The Ark)
In Australia in 1987, Tegan Jovanka's father was hospitalised after a snake bite. (PROSE: Encounter on Burnt Snake Flat)
In Haiti in 1915, Charles Oscar Etienne was killed by a snake intended for the Doctor. (PROSE: White Darkness)
One snake which resided in Twycross Zoo was draped around Wanda's shoulders when she first met the Tenth Doctor and Rose Tyler; Rose was afraid of it. (COMIC: Untitled)
Snakes on other planets
A type of giant snake was native to Metebelis III at some point in its history. (TV: The Green Death)
Giant purple Ice Snakes lived on Centuria. (COMIC: Enemy Mine)
The Church once fought lava snakes. (TV: The Time of Angels)
A giant species of snake called the Oroborus was able to consume time. (TV: Oroborus)
Another giant species of snake known as the Sythaks were native to the swamps of Palliox, a planet near Trion. In 1905, the travelling showman Thaddeus P. Winklemeyer had two Sythaks in his freakshow. (AUDIO: Freakshow)
In a jungle on an unnamed planet, Gillian was threatened by a hooded snake, but the First Doctor saved her by throwing his coat over it. (COMIC: The Didus Expedition)
As part of his magic act for the Gods of Ragnarok in the Dark Circus, the Seventh Doctor appeared to conjure a snake, then transform it into his umbrella. (TV: The Greatest Show in the Galaxy)
Colony Sarff was a creature comprised of many snakes working together to mimic one humanoid individual. (TV: The Magician's Apprentice / The Witch's Familiar)
Usages
On Thoros Beta, sand snakes were consumed by the Mentors, such as Kiv. (TV: Mindwarp)
On Earth snake skin was sometimes used to to make shoes. (PROSE: Eternity Weeps, Mad Dogs and Englishmen)
Emotive responses
Styre's experiments into fear on Sarah Jane Smith caused her to hallucinate a snake on her arm. (TV: The Sontaran Experiment) Polly Wright was also always afraid of snakes. (AUDIO: House of Cards)
When the Mara took physical form away from Dark Places of the Inside it took the form of a giant snake, both as a tattoo and as a physical snake. (TV: Kinda, Snakedance)
Clara Oswald confessed she hated snakes. (PROSE: Into the Nowhere)
References
In an alternate Paris of 1804, Randolph Eging compared the DNA molecule to two snakes coiled together. (PROSE: The Man in the Velvet Mask)
In Greek mythology, Medusa (TV: The Mind Robber) and the Gorgon COMIC: The Gaze of the Gorgon) had snakes for hair.
Snakes and ladders was a game which used images of snakes. (PROSE: Cat's Cradle: Warhead)
The Ouroboros was the symbol of a snake eating its own tail. (PROSE: Falls the Shadow)
The lower half of Qataka's cybernetic body was that of a snake. (PROSE: Timewyrm: Genesys)