Pre-regeneration

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The First Doctor admits to his fear of change. (TV: Twice Upon a Time [+]Loading...["Twice Upon a Time (TV story)"])

For a Time Lord, to be pre-regeneration - that is, having not yet regenerated - was a sign of youth. (GAME: The Heir of Gallifrey [+]Loading...["The Heir of Gallifrey (game)"])

One source stated that Time Lords were born with just one heart and grew a second heart on regeneration. This included the Doctor, who in their first incarnation had only one heart. (PROSE: The Man in the Velvet Mask [+]Loading...["The Man in the Velvet Mask (novel)"]) Other accounts showed Time Lords having two hearts in their original incarnation, such as the Doctor (AUDIO: Frostfire [+]Loading...["Frostfire (audio story)"], The Abandoned [+]Loading...["The Abandoned (audio story)"]) and Jenny. (TV: The Doctor's Daughter [+]Loading...["The Doctor's Daughter (TV story)"]) Tegan Jovanka was under the belief that the second heart of a Time Lord was only developed upon the first regeneration, much to the surprise of Leela, who believed that a Time Lord always had two hearts, with neither being sure who was correct. (AUDIO: Time in Office [+]Loading...["Time in Office (audio story)"])

Klyst assured Louis following his first regeneration that the first was always more painful than subsequent ones. (AUDIO: Unregenerate! [+]Loading...["Unregenerate! (audio story)"])

The First Doctor avoided his regeneration and the change of appearance that came with it as it neared, maintaining that he had "the courage and the right to live and die as [himself]". However, he later admitted to the Twelfth Doctor that he did so out of fear. It was through this encounter with his future self, whose circumstances led him to wish to stop "being somebody else", that the First Doctor was convinced to accept his regeneration into the Second Doctor, whilst the Twelfth Doctor accepted his regeneration into the Thirteenth Doctor. (TV: Twice Upon a Time [+]Loading...["Twice Upon a Time (TV story)"])