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The Thirteenth Doctor was the first female incarnation of the Doctor.
Biography
A day to come
While suffering with the common cold, the Twelfth Doctor, overreacting to the illness, considered the possibility of regenerating. (COMIC: The Day at the Doctors)
After the Monk invasion, the Twelfth Doctor needed to know if his companion, Bill Potts, was under the control of the Monks, and deceived her into shooting him in a rage to see if she had succumbed to the mind control, faking his regeneration to complete the illusion. He made it look like the process had started, but emerged as himself to show her that she had been deceived by him. (TV: The Lie of the Land)
Post-regeneration
The Twelfth Doctor had been gravely wounded by the Cybermen on the Mondasian colony ship. In spite of his life-threatening injury, the Doctor, feeling tired of "being someone else", chose to purposefully halt his regenerative process. (TV: The Doctor Falls) However, following an encounter with his first incarnation, who had held similar reservations before his own regeneration, and the Testimony, the Doctor ultimately conceded that another regeneration would not "kill [him]."
Returning to the TARDIS, the Doctor addressed himself or rather his successor, offering words of advice before finally regenerating. Immediately after, the Doctor examined her new face in a reflection, to which she simply exclaimed "Brilliant!" However, before she could continue, the TARDIS suddenly fell out of her control, and the Doctor found herself falling out through the TARDIS' now opened doors to the Earth below. (TV: Twice Upon a Time)
Appearance
The Thirteenth Doctor's hands were noticably smaller than those of her predecessor, resulting in the ring that he had worn falling onto the floor upon regeneration. (TV: Twice Upon a Time)