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History
Louise had read about a similar species to the Cyberons who had attempted invaded Earth several times in the P.R.O.B.E. Archive. (PROSE: The Last Dose)
21st century
In 2000, P.R.O.B.E. eradicated a computer virus that had removed all the vowels from every electronic device on the planet, (PROSE: The Last Dose) which had been released by the Cybermen. (PROSE: Vrs) Louise Bayliss knew that the groups from Geneva or Canary Wharf were "nowhere to be seen". (PROSE: The Last Dose)
One damaged Cyberon arrived in the year 2000 and began converting certain doctors, for them to begin conducting "tests" in order to get the public to accept Cyberon as a miracule cure for afflictions such as dementia, as a means to ensure the survival of the Cyberons by mass conversion. It failed at the hands of Lauren Anderson who fought back against Tom Mordley, one of the lead doctors behind the drug. After Lauren had believed she had killed Tom and turned herself in at a police station, (PROSE: Cyberon) her claims that Cyberon was alien caught the attention of P.R.O.B.E.; shortly after, Patricia Haggard requested the help of Louise Bayliss, who had transferred from P.R.O.B.E. to the Home Office five years prior at the request of Sir Andrew Williams. Patricia sent Louise to a PKD facility to oversee the containment of the drug so the teams from Geneva and Canary Wharf didn't butcher anything.
At the facility in the outskirts of London, Louise encountered Tom, who had been restored to life after Lauren killed him. Tom had broken into the facility to retrieve more batches of the Cyberon drug in order to keep the spread going, and Louise followed Tom into an unsecured part of the facility, where she witnessed Tom kill Albert, the first to have taken the Cyberon drug, as he had stopped taking said drug. Tom began speaking to the original Cyberon, who then commanded Tom to kill Louise, but as Tom went to kill her, he was repelled by Louise's gold necklace. She used this to drive the Cyberon from out of Tom, as it interfered with the Cyberon's connection to his nervous system. In his freedom, he destroyed the original Cyberon, although Tom then succumbed to the trauma he had endured and died.
The remaining batches of the drug where then secured and transported to the Vault in Northumberland by UN soldiers, under Louise's guidence. Louise returned to Ashley House, where Patricia informed her of Tom's upcoming funeral and the cover story that he was a con man. Louise asked if there was a chance she could return to P.R.O.B.E., but Patricia told her that Sir Andrew would object, not to mention P.R.O.B.E. barely even had the budget to keep their other member. Louise then travelled to Lauren Anderson's flat, where she told Lauren of the heroism performed by Tom in his last minutes, and to assure Lauren she is a good person and should return to her job as a doctor. (PROSE: The Last Dose)
P.R.O.B.E. was present for the funeral of Tom, where he was entombed in a golden coffin which was sealed in the ground with concrete, and they introduced themselves to Sarah and Brittany Mordley. (PROSE: Silver-Tongued Liars)